Madalsa Sharma was born on 26 September to film producer and director Subhash Sharma and actress Sheela Sharma. After completing her schooling from Marble Arch school, she studied English Literature at the Mithibai College Mumbai.

Recently, Madalsa gained lot of popularity by her daring performance in the reality show Super 2 by E TV Telugu, produced by Vajayanthi Films.

Her Tamil release Pathaiyeram Kodi was followed by a number of commercials, appearances, endorsements etc.

Madalsa did a commercial directed by S. S. Rajamouli, "Emami Navratna talc", where her look was appreciated.

She is currently working on a short film for Cannes Film Festival.

Now, She is debuting on Television by playing role of Kavya Zaveri in Anupamaa.