Nausheen grew up in a Catholic society and school, then went to a Sindhi college. Nausheen is a commerce graduate from MMK College in Bandra, Mumbai, After school she started modelling, a career which lasted two years. Sardar appeared in the video album Ocean Queen, Altaf Raja's "Pehle to Kabhi Kabhi Gum Tha", Star best Sellers' X-zone and as a TV host. Internationally, she also acted for many Pakistani television serials, among which Kuch Dil Se is most credited. She is also present in the serial Beendh Banunga Ghodi Chadunga on Imagine TV. She was seen in Sony Television’s reality show, Mr. and Mrs. TV and another reality show Arrange Marriage on Sahara Samay. She has also played the role of main protagonist in the TV Serial KKusum on Sony Entertainment Television.